Lucie Mé · Yorkville + Fairview Mall
HArmonyCa in Toronto
The hybrid injectable from Allergan Aesthetics. Immediate lift from hyaluronic acid, lasting collagen renewal from calcium hydroxylapatite. At our Yorkville and Fairview Mall clinics.
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Why HArmonyCa?
An immediate lift, then lasting collagen
HArmonyCa is a hybrid injectable from Allergan Aesthetics that combines two materials in a single syringe: cross-linked hyaluronic acid and calcium hydroxylapatite microspheres. The hyaluronic acid works the way a dermal filler does, plumping and lifting the treated area on the day of treatment. The calcium hydroxylapatite works differently. Its microspheres stay in the tissue and act as a scaffold that activates fibroblasts, the cells responsible for producing collagen, so the skin gradually builds new structure of its own over the following months.
Until now these were two separate treatment categories: fillers for immediate volume, biostimulators for gradual collagen renewal. HArmonyCa was the first product to combine them, and it arrived in Canada in 2026 with Health Canada authorization. It's injected into the deep dermal and subdermal layers of the face, and the formulation includes lidocaine to keep the treatment comfortable. Results from the collagen phase build for months and can last up to 18 months.
The first step
What happens at a HArmonyCa consultation?
The consultation establishes whether HArmonyCa is the right treatment for what you want to change. The clinician assesses the mid and lower face: cheek volume, jawline definition, the pre-jowl area, and overall skin laxity. HArmonyCa suits people who want both lift and skin quality improvement from one treatment. If the concern is a single deep line, a standard filler may be the better tool; if it's gradual collagen renewal without any immediate change, a biostimulator such as Sculptra may fit better. The consultation is where that call is made.
At Lucie Mé, consultations are complimentary. Medical history is reviewed before any injectable treatment, including allergies, bleeding disorders, and any active skin inflammation in the treatment area, all of which affect whether treatment can go ahead. The number of syringes for your treatment plan, and what it will cost, is confirmed at the consultation before anything is booked.
Lucie Mé
Restore. Rejuvenate. Enhance.
At Lucie Mé we specialise in the most advanced non-surgical cosmetic and body contouring treatments, delivered by medically trained professionals. Two Toronto clinics: Yorkville at Holt Renfrew Centre, and Fairview Mall in North York. Established 2010. Complimentary consultations.
What to expect
From injection to full result
The treatment
HArmonyCa is injected into the deep dermal and subdermal layers of the face using a needle or cannula, depending on the area and the goal. The product itself contains lidocaine, a local anaesthetic, so the treatment stays comfortable as it progresses. The clinician works through the planned areas, typically the cheeks, jawline, and pre-jowl region, shaping the lift as they go.
The immediate lift
The hyaluronic acid component works on the day. You leave with a visible lift in the treated areas, the same way a dermal filler behaves. Some swelling, tenderness, or bruising at the injection points is common and settles over the following days. Standard advice is to avoid strenuous exercise for 24 hours and direct sun exposure for the first week.
The collagen phase
The calcium hydroxylapatite microspheres go to work over the following months. Studies measured increased tissue density and firmness at 60 to 90 days, and confirmed increased collagen in treated areas at 180 days. This is the part of the result your own skin produces, and it's why the overall effect can last up to 18 months.
Inside the syringe
This treatment combines two materials
The hyaluronic acid in HArmonyCa is a cross-linked gel, the same class of material used in dermal fillers. It holds water, adds volume, and lifts the tissue it's placed in from the moment it's injected. This is what makes the result visible on the day of treatment rather than months later. Over time the gel gradually breaks down, which is by design: as the hyaluronic acid softens, the new collagen built by the calcium hydroxylapatite is taking over the structural work.
Calcium hydroxylapatite is a biocompatible material used in medicine for decades. In HArmonyCa it takes the form of microspheres 25 to 45 microns across, suspended through the gel. Once in the tissue they act as a scaffold that activates fibroblasts, the cells that produce collagen, so the skin builds new collagen of its own around them. This is the slow half of the result: firmer, denser tissue measurable from around two to three months and building from there.
How it compares
HArmonyCa, dermal fillers, and Sculptra
Dermal fillers are hyaluronic acid gels. They add volume and lift immediately, and the result gradually softens as the gel breaks down over months. Sculptra sits in the other category: it's a biostimulator made from poly-L-lactic acid that triggers your own collagen production, so the change appears gradually over several months with little visible difference on the day. Each approach has a trade-off. Fillers give an instant result that your body eventually clears; biostimulators give a result your body builds but makes you wait for it.
HArmonyCa combines both mechanisms in a single product: filler-style hyaluronic acid for the day-one lift and calcium hydroxylapatite microspheres for the collagen renewal that follows. That makes it a strong fit for the mid and lower face, where both volume loss and skin laxity tend to appear together. It doesn't replace the other injectables. Botox still handles expression lines, fillers still handle precise volume work such as lips, and the consultation is where the right tool, or combination, is decided.
Common questions
What people ask about HArmonyCa
What is HArmonyCa?
HArmonyCa is a hybrid injectable from Allergan Aesthetics, the company behind Botox and the Juvéderm filler range. It combines two materials in one syringe: cross-linked hyaluronic acid, which lifts and adds volume immediately the way a dermal filler does, and calcium hydroxylapatite microspheres, which stimulate your own collagen production over the following months. It was the first product to combine the two categories, and the Canadian version, HArmonyCa with Lidocaine, includes a local anaesthetic in the formulation for comfort. It's injected into the deep dermal and subdermal layers of the face, most often the cheeks, jawline, and pre-jowl area, by a trained medical professional.
How does HArmonyCa work?
HArmonyCa works through two mechanisms running on different clocks. The hyaluronic acid component is a cross-linked gel that holds water and lifts the tissue it's injected into, so there's a visible change on the day of treatment. The calcium hydroxylapatite component is made of microspheres 25 to 45 microns across that remain in the tissue and act as a scaffold, activating fibroblasts, the cells that produce collagen. Over the following months the skin builds new collagen around the microspheres. Studies measured increased tissue density and firmness at 60 to 90 days and confirmed increased collagen in treated areas at 180 days, which is why the result matures over time rather than peaking on day one.
How is HArmonyCa different from regular dermal fillers?
A regular dermal filler is hyaluronic acid alone. It gives an immediate result, and when the gel breaks down the result goes with it. HArmonyCa keeps that immediate filler effect but adds calcium hydroxylapatite, a biostimulator that prompts your skin to produce new collagen of its own. So while the hyaluronic acid gradually softens, the new collagen is building, and that structural change belongs to your own tissue rather than to a product that gets cleared. In practice this makes HArmonyCa suit a different goal than a standard filler: it's less about placing precise volume in one spot and more about lifting and firming the mid and lower face as a whole. Allergan reports results lasting up to 18 months.
How long does HArmonyCa last?
Allergan reports that HArmonyCa results last up to 18 months. The shape of the result changes across that time. The hyaluronic acid lift is strongest in the early weeks and gradually softens as the gel is broken down by the body. The collagen phase moves in the opposite direction: measurable increases in tissue density appear from around 60 to 90 days, with increased collagen confirmed in studies at 180 days, and that firmness carries the result through the later months. Because the collagen is your own tissue, the treated area doesn't simply snap back to its starting point when the product itself is gone. Whether and when a repeat treatment makes sense is reviewed at a follow-up consultation.
Is HArmonyCa approved in Canada?
Yes. HArmonyCa with Lidocaine received Health Canada authorization, and Allergan Aesthetics launched it in Canada in May 2026 as the first dual-action collagen-stimulating injectable of its kind on the Canadian market. Before that, the product had already been in use internationally, with approvals in more than 30 countries since its original launch. In Canada it's a professional-use injectable, administered by trained medical professionals, and Allergan maintains a clinic locator for verified providers. As with any injectable, the product itself being authorized is only half the picture; the assessment, injection technique, and follow-up are what determine the result, which is why treatment starts with a consultation rather than a booking.
Is there downtime after HArmonyCa?
Downtime is minimal for most people. The common side effects are the ones familiar from any injectable: bruising, swelling, tenderness, and sometimes itching at the injection points, which typically settle over a few days. The product contains lidocaine, so the treatment itself stays comfortable. Standard aftercare advice is to avoid strenuous exercise for 24 hours and direct sun exposure for the first week. The immediate lift is visible straight away, though the treated area can look slightly fuller than the final early result while any swelling settles. The collagen phase that follows involves no downtime at all; the tissue changes happen gradually over the following months without anything visible on the surface.
How much does HArmonyCa cost in Toronto?
HArmonyCa is priced per syringe, and the number of syringes depends on the areas being treated and the degree of change you're after. A treatment covering the cheeks, jawline, and pre-jowl area on both sides uses more product than a single-area treatment, so the honest answer to cost starts with an assessment rather than a flat number. As a newer premium injectable from Allergan, it sits at the higher end of the injectable range in most Toronto clinics. At Lucie Mé, the consultation is complimentary: the clinician confirms whether HArmonyCa is the right treatment, maps the syringe count for your plan, and gives you the exact cost before anything is booked.
Bookings
Ready when you are.
Complimentary consultations at both clinics. Book online and we'll be in touch to confirm a time that suits you.
Two clinics in Toronto
Where to have this treatment
Yorkville
HArmonyCa treatments in Yorkville at the Holt Renfrew Centre.
Holt Renfrew Centre, 50 Bloor Street West, Unit C10
North York
HArmonyCa in North York at Fairview Mall, direct from Don Mills station.
CF Fairview Mall, 1800 Sheppard Avenue East